| Day | Week | Home | Result | Away |
|---|---|---|---|---|
| 2025-09-06 | 1 | Bayern München | 2 - 0 | Bayer Leverkusen |
| 2025-09-15 | 2 | Bayer Leverkusen | 3 - 2 | Union Berlin |
| 2025-09-21 | 3 | Nürnberg | 0 - 1 | Bayer Leverkusen |
| 2025-09-25 | 4 | Bayer Leverkusen | 2 - 1 | Eintracht Frankfurt |
| 2025-10-12 | 6 | Hoffenheim | 0 - 2 | Bayer Leverkusen |
| 2025-10-19 | 7 | Bayer Leverkusen | 1 - 5 | Wolfsburg |
| 2025-11-02 | 8 | Carl Zeiss Jena | 2 - 4 | Bayer Leverkusen |
| 2025-11-05 | 9 | Bayer Leverkusen | 2 - 1 | Hamburger SV |
| 2025-11-10 | 10 | Freiburg | 2 - 1 | Bayer Leverkusen |
| 2025-11-22 | 11 | Bayer Leverkusen | 0 - 1 | SGS Essen |
| 2025-12-06 | 12 | Bayer Leverkusen | 3 - 2 | RB Leipzig |
| 2025-12-12 | 13 | Werder Bremen | 1 - 0 | Bayer Leverkusen |
| 2025-12-22 | 14 | Bayer Leverkusen | 0 - 3 | Bayern München |
| 中止 | 5 | Köln | - | Bayer Leverkusen |
Bayer Leverkusen
2025-26シーズン